A Convenient Synthesis of Oxazolines and Imidazolines from Aromatic Aldehydes with Pyridinium Hydrobromide Perbromide in Water
*Department of Chemistry, Fukushima Medical University, Hikariga-oka, Fukushima 960-1295, Japan, Email: ssayamafmu.ac.jp
S. Sayama, Synlett, 2006, 1479-1484.
Various 2-oxazolines were prepared from aromatic aldehydes and 2-aminoethanol with pyridinium hydrobromide perbromide in water at room temperature. The reaction of aromatic aldehydes with ethylenediamine gave 2-imidazolines in good yields under the same reaction conditions.