Revisiting the Passerini Reaction under Eco-Friendly Reaction Conditions
Carlos Kleber Z. Andrade*, Sayuri Cristina S. Takada, Paulo Anselmo Z. Suarez, Melquizedeque B. Alves
*Laboratório de Química Metodológica e Orgânica Sintética (LaQMOS),
Instituto de Química, Universidade de Brasília, C.P. 4478, 70910-970, Brasília,
DF, Brazil, Email: ckleber
unb.br
C. K. Z. Andrade, S. C. S. Takada, P. A. Z. Suarez, M. B. Alves, Synlett, 2006, 1539-1541.
DOI: 10.1055/s-2006-941606
Abstract
α-Acyloxy carboxamides were easily obtained in one step by a Passerini reaction between carboxylic acids, aldehydes and isocyanides in ionic liquids or polyethyleneglycol as green reaction media.
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Key Words
Passerini reaction, ionic liquids, multicomponent reactions, polyethylene glycol, green chemistry
ID: J60-Y2006-4470
