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An Efficient Catalyst System for Palladium-Catalyzed Borylation of Aryl Halides with Pinacolborane

Miki Murata*, Tomoko Sambommatsu, Shinji Watanabe, Yuzuru Masuda

*Department of Materials Science, Kitami Institute of Technology, Kitami 090-8507, Japan, Email:

M. Murata, T. Sambommatsu, S. Watanabe, Y. Masuda, Synlett, 2006, 1867-1870.

DOI: 10.1055/s-2006-947365

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The combination of Pd(dba)2 and bis(2-di-tert-butyl­phosphinophenyl)ether is an efficient catalyst system for the cross­coupling of pinacolborane with aryl bromides. This system enables the synthesis of ortho-, meta-, and para-substituted electron-rich and -deficient arylboronates. A temperature of 120°C was required for the conversion of electron-rich aryl chlorides.

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Key Words

boron, arylboronates, palladium, catalysis, cross-coupling, ligands

ID: J60-Y2006-4530