Remarkably Chemoselective Reduction of Unmodified Baylis-Hillman Adducts by InCl3/NaBH4: Application to the Stereoselective Synthesis of Trisubstituted Alkenones Including Two Alarm Pheromones
Biswanath Das*, Joydeep Banerjee, Nikhil Chowdhury, Anjoy Majhi, Harish Holla
*Organic Chemistry Divison I, Indian Institute of Chemical Technology, Hyderabad, Email: biswanathdasyahoo.com
B. Das, J. Banerjee, N. Chowdhury, A. Majhi, H. Holla, Synlett, 2006, 1879-1882.
A novel, convenient and stereoselective synthesis of trisubstituted E-alkenones has been achieved by InCl3-mediated chemoselective reduction of Baylis-Hillman adducts with NaBH4 as reductant.
see article for more examples
Enones, Baylis-Hillman Adducts, Indium, Sodium Borohydride