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Cellulose-Supported Copper(0) Catalyst for Aza-Michael Addition

K. Rajender Reddy*, Nadakudity S. Kumar

*Inorganic and Physical Chemistry Division, Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500 007, India, Email:

K. R. Reddy, N. S. Kumar, Synlett, 2006, 2246-2250.

DOI: 10.1055/s-2006-949623

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Cellulose-supported copper(0) efficiently catalyzes aza-Michael reactions of N-nucleophiles, such as amines and imidazoles with α,β-unsaturated compounds to produce the corresponding β-amino compounds and N-substituted imidazoles in excellent yields. The recovered catalyst can be used for several cycles with consistent activity.

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Key Words

cellulose, copper, aza-Michael, amines, α,β-unsaturated compounds, β-amino compounds

ID: J60-Y2006-4600