AgI-PEG400-KI Catalyzed Environmentally Benign Synthesis of Aroyl Cyanides Using Potassium Hexacyanoferrate(II) as the Cyanating Agent
Zheng Li*, Shengyi Shi, Jingya Yang
*Gansu Key Laboratory of Polymer Materials, College of Chemistry and
Chemical Engineering, Northwest Normal University, Lanzhou, Gansu, 730070, P. R.
of China, Email: lizheng
nwnu.edu.cn
Z. Li, S. Shi, J. Yang, Synlett, 2006, 2495-2497.
DOI: 10.1055/s-2006-950407
Abstract
A practical cyanation of aroyl chlorides was performed in DMF at room temperature with 0.2 equivalent of a non-toxic cyanide source, 3 mol% AgI, 4 mol% PEG-400, and 3 mol% KI as the catalyst system. The corresponding aroyl cyanides were prepared in good yields.
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Key Words
green chemistry, catalysis, synthesis, phase-transfer catalysis, cyanation
ID: J60-Y2006-4650
