Peterson Allenation Using (Z)-(1-Lithio-1-alkenyl)trimethylsilanes
Akira Tsubouchi, Takashiro Kira, Takeshi Takeda*
*Department of Applied Chemistry, Graduate School of Engineering, Tokyo
University of Agriculture and Technology, Koganei, Tokyo 184-8588, Japan, Email:
takeda-t
cc.tuat.ac.jp
A. Tsubouchi, T. Kira, T. Takeda, Synlett, 2006, 2577-2580.
DOI: 10.1055/s-2006-951474
Abstract
Lithium alkoxides of β-silylallylic alcohols underwent the Peterson elimination in DMF to give allenes. A one pot process for a Peterson allenation reaction of carbonyl compounds using (Z)-(1-lithio-1-alkenyl)trimethylsilanes is described.
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T. Shono, K. Ito, A. Tsubouchi, T. Takeda, Org. Biomol. Chem., 2005, 3, 2914-2916.
Key Words
alcohols, allenes, carbonyl, elimination, silicon, Peterson Olefination
ID: J60-Y2006-4660
