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Catalytic Reductive Etherification of Ketones with Alcohols at Ambient Hydrogen Pressure: A Practical, Waste-Minimized Synthesis of Dialkyl Ethers

Lukas J. Gooßen*, Christophe Linder

*Institut für Chemie - Organische Chemie, TU Kaiserslautern, Erwin-Schrödinger-Straße, Geb. 54, 67663 Kaiserslautern Email:

L. J. Gooßen, C. Linder, Synlett, 2006, 3489-3491.

DOI: 10.1055/s-2006-956484

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A heterogeneous platinum catalyst efficiently mediates the reductive etherification of ketones at ambient hydrogen pressure. In this transformation, water is released as the only by-product, and this is trapped with molecular sieves.

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Key Words

ethers, reductive etherification, platinum, catalysis, hydrogenation

ID: J60-Y2006-4850