Mild Oxidation of Alcohols with o-Iodoxybenzoic Acid (IBX) in Water/Acetone Mixture in the Presence of β-Cyclodextrin
K. Surendra, N. Srilakshmi Krishnaveni, M. Arjun Reddy, Y. V. D. Nageswar and K. Rama Rao*
*Organic Chemistry Division-I, Indian Institute of Chemical Technology,
Hyderabad-500 007, India, Email: ramaraok
iict.res.in
K. Surendra, N. Srilakshmi Krishnaveni, M. Arjun Reddy, Y. V. D. Nageswar, K. Rama Rao, J. Org. Chem., 2003, 68, 2058-2059.
DOI: 10.1021/jo026751w
Abstract
A mild and efficient oxidation of alcohols with o-iodoxybenzoic acid (IBX) is catalyzed by β-cyclodextrin in a water/acetone mixture (86:14). Various alcohols were oxidized at room temperature in excellent yields.
see
article for more examples
Highly Selective Oxidative Cleavage of β-Cyclodextrin-Epoxide/Aziridine Complexes with IBX in Water
K. Surendra, N. S. Krishnaveni, M. A. Reddy, Y. V. D. Nageswar, K. R. Rao, J. Org. Chem., 2003, 68, 9119-9121.
Key Words
IBX, oxidation, hypervalent iodine reagents, ketones, aldehydes, hydroxyketones
ID: J42-Y2003-180
