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Facile Oxidation of Aldehydes to Acids and Esters with Oxone

Benjamin R. Travis, Meenakshi Sivakumar, G. Olatunji Hollist and Babak Borhan*

*Department of Chemistry, Michigan State University, East Lansing, Michigan 48824, Email:

B. R. Travis, M. Sivakumar, G. O. Hollist, B. Borhan, Org. Lett., 2003, 5, 1031-1034.

DOI: 10.1021/ol0340078

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Highly efficient, mild, and simple protocols allow the oxidation of aldehydes to carboxylic acids and esters utilizing Oxone as the sole oxidant. These reactions may prove to be valuable alternatives to traditional metal-mediated oxidations.

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Key Words

Oxidation, Oxone, Potassium peroxymonosulfat, Carboxylic Acids, Esters

ID: J54-Y2003-400