Organic Chemistry Portal

Abstracts

Search:

Influence of HMPA on Reducing Power and Reactivity of SmBr2

Brian W. Knettle and Robert A. Flowers, II*

*Department of Chemistry, University of Toledo, Toledo, Ohio 43606, Email: rfloweruoft02.utoledo.edu

B. W. Knettle, R. A. Flowers, II, Org. Lett., 2001, 3, 2321-2324.

DOI: 10.1021/ol0160957


Abstract

The combination of HMPA and SmBr2 in THF is a powerful reductant that is capable of reducing ketimines and alkyl chlorides at room temperature. The structure of this reductant has not been established.

see article for more reactions



Key Words

low-valent samarium reagents, reduction of imines, dehalogenation


ID: J54-Y2001-300