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Utility of Neodymium Diiodide as a Reductant in Ketone Coupling Reactions

William J. Evans,* Penny S. Workman, and Nathan T. Allen

*Department of Chemistry, University of California-Irvine, Irvine, California 92697-2025, Email:

W. J. Evans, P. S. Workman, N. T. Allen, Org. Lett., 2003, 5, 2041-2042.

DOI: 10.1021/ol030033u


NdI2 is viable one-electron reducing agent in coupling reactions between alkyl chlorides and carbonyl compounds.

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Key Words

Reductive Coupling, Alcohols, Ketones, Aldehydes, Neodymium

ID: J54-Y2003-440