R3Al-R'3SiOTf: Novel and Powerful Reagent System for Stereospecific Alkylation-Silylation Reactions of Epoxides
Ponnusamy Shanmugam and Masaaki Miyashita*
*Division of Chemistry, Graduate School of Science, Hokkaido University, Sapporo 060-0810, Japan, Email: miyasitasci.hokudai.ac.jp
P. Shanmugam, M. Miyashita, Org. Lett., 2003, 3265-3268.
DOI: 10.1021/ol035075x
Abstract
A one-pot alkylation-silylation reaction of various epoxides with R3Al-R'3SiOTf occurs stereospecifically to give the corresponding alkylation-silylation products in excellent yields.
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Key Words
epoxides, alkylation, silylation
ID: J54-Y2003-530