An Improved Protocol for the RuO4-Catalyzed Dihydroxylation of Olefins
Bernd Plietker* and Meike Niggemann
*Institut für Organische Chemie, Universität Stuttgart,
Pfaffenwaldring 55, 70569 Stuttgart, Germany, Email: bernd.plietkeroc.uni-stuttgart.de
B. Plietker, M. Niggemann, Org. Lett., 2003, 3353-3356.
DOI: 10.1021/ol035335a
Abstract
An improved protocol for the RuO4-catalyzed syn-dihydroxylation uses only 0.5 mol% catalyst under acidic conditions. Various olefins can be hydroxylated in good to excellent yields with only minor formation of side products.
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article for more examples
proposed mechanism
The acid accelerated ruthenium-catalysed dihydroxylation. Scope and limitations
B. Plietker, M. Niggemann, A. Pollrich, Org. Biomol. Chem., 2004, 2, 1116-1124. DOI: 10.39/b316546a
Key Words
Dihydroxylation, Ruthenium, Sodium Periodat
ID: J54-Y2003-540