A Well-Defined Complex for Palladium-Catalyzed Aerobic Oxidation of Alcohols: Design, Synthesis, and Mechanistic Considerations
David R. Jensen, Mitchell J. Schultz, Jaime A. Mueller, Matthew S. Sigman*
*Department of Chemistry, University of Utah, 315 S. 1400 East, Salt Lake City, UT 84112, USA, Email: sigmanchem.utah.edu
D. R. Jensen, M. J. Schultz, J. A. Mueller, M. S. Sigman, Angew. Chem. Int. Ed., 2003, 42, 3810-3813.
DOI: 10.1002/anie.200351997 (free Supporting Information)
A robust and effective Pd catalyst for the aerobic oxidation of various alcohols has been discovered. Using a slightly higher concentration of acetic acid as additive and extending the reaction times, the oxidation can be carried out under ambient atmosphere of air.
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alcohols, oxidation, aldehydes, ketones, oxygen, palladium, reaction mechanisms