A CAN-Induced Cyclodimerization-Ritter Trapping Strategy for the One-Pot Synthesis of 1-Amino-4-aryltetralins from Styrenes
Vijay Nair*, Roshini Rajan and Nigam P. Rath
*Organic Chemistry Division, Regional Research Laboratory (CSIR),
Trivandrum, India, and Department of Chemistry, University of Missouri, St.
Louis, Missouri 63121, Email: gvn
csrrltrd.ren.nic.in
V. Nair, R. Rajan, N. P. Rath, Org. Lett., 2002, 4, 1575-1577.
DOI: 10.1021/ol0257934
Abstract
A facile one-pot CAN-induced cyclodimerization of various styrenes in acetonitrile or acrylonitrile gave 1-amino-4-aryltetralin derivatives.
see article for more examples
proposed mechanism
Key Words
Ritter Reaction, Cerium Ammonium Nitrate
ID: J54-Y2002-780
