Beckmann Rearrangement of Oximes under Very Mild Conditions
Lidia De Luca, Giampaolo Giacomelli* and Andrea Porcheddu
*Dipartimento di Chimica, Università degli Studi di Sassari, Via Vienna 2,
I-07100 Sassari, Italy, Email: ggp
uniss.it
L. De Luca, G. Giacomelli, A. Porcheddu, J. Org. Chem., 2002, 67, 6272-6274.
DOI: 10.1021/jo025960d
Abstract
Different ketoximes, which are prepared from the corresponding ketones, undergo the Beckmann rearrangement at room temperature in excellent yields upon treatment with 2,4,6-trichloro[1,3,5]triazine in N,N-dimethylformamide. Nitriles are obtained from aldoximes using the same procedure.
see article for more examples
proposed
mechanism
Key Words
Beckmann Rearrangement, Nitriles
ID: J42-Y2002-790
