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Bulky Trialkylsilyl Acetylenes in the Cadiot-Chodkiewicz Cross-Coupling Reaction

Joseph P. Marino* and Hanh Nho Nguyen

*Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, Email:

J. P. Marino, H. N. Nguyen, J. Org. Chem., 2002, 67, 6841-6844.

DOI: 10.1021/jo025745x


Bulky trialkylsilyl-protected alkynes underwent the Cadiot-Chodkiewicz cross-coupling reaction with different bromoalkynes to form various synthetically useful unsymmetrical diynes in good yields.

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Key Words

Cadiot-Chodkiewicz Coupling

ID: J42-Y2002-840