Oxidation of aldimines to amides by m-CPBA and BF3ˇOEt2
Gwang-il An, Misoo Kim, Jin Yeon Kim and Hakjune Rhee*
*Department of Chemistry, Hanyang University, Ansan, Kyunggi-Do 425-791, Republic of Korea, Email: hrheehanyang.ac.kr
G. An, M. Kim, J. Y. Kim, H. Rhee, Tetrahedron Lett., 2003, 44, 2183-2186.
Several amides were obtained in high yields by an efficient method from the corresponding imines which are readily prepared from aldehydes. This procedure involves the oxidation of aldimines with m-CPBA and BF3ˇOEt2. In this reaction, the product is strongly influenced by the electron releasing capacity of the aromatic substituent.
see article for more examples