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A two step synthesis of 2-oxo-2-vinyl 1,3,2-dioxaphospholanes and -dioxaphosphorinanes

Michel Maffei* and Gérard Buono

*Laboratoire des Organo-Phosphorés (UMR 6009 du C.N.R.S.), B.P. 552, Faculté de Saint Jérôme, Avenue Escadrille Normandie Niémen, 13397, Marseille Cedex 20, France, Email:

M. Maffei, G. Buono, Tetrahedron, 2003, 59, 8821-8825.

DOI: 10.1016/j.tet.2003.08.067


A two step procedure involving a transesterification between a diol and diethyl phosphite followed by a palladium-catalyzed coupling of the so-obtained cyclic phosphite with vinyl bromide gave vinyl phosphonates in good yields.

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Key Words

phosphites, phosphonates

ID: J72-Y2003-1000