Microwave-Assisted Amination from Aryl Triflates without Base and Catalyst
Gang Xu and Yan-Guang Wang*
*Department of Chemistry, Zhejiang University, Hangzhou 310027, P. R. China, Email: orgwygzju.edu.cn
G. Xu, Y.-G. Wang, Org. Lett., 2004, 6, 985-987.
DOI: 10.1021/ol049963j (free Supporting Information)
Aryl triflates substituted with both electron-poor and electron-rich groups are effectively converted to the corresponding anilines under microwave irradiation in 1-methyl-2-pyridone (NMP) without base and catalyst. It is noteworthy that halogenated aryl triflates chemoselectively afford halogenated anilines.
see article for more examples