A Catalytic Oxidative Esterification of Aldehydes Using V₂O₅-H₂O₂

Rangam Gopinath and Bhisma K. Patel*

*Department of Chemistry, Indian Institute of Technology, Guwahati-781 001, India, Email: pateliitg.ernet.in

R. Gopinath, B. Patel, Org. Lett., 2000, 2, 577-579.

DOI: 10.1021/ol990383+

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Abstract

Aldehydes undergo oxidative transformation to the methyl esters in methanol as solvent upon treatment with catalytic amounts of vanadium pentoxide in combination with hydrogen peroxide. This method features mild reaction conditions, short reaction times, high efficiencies, cost-effectiveness, and facile isolation of the desired products.

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proposed mechanism

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Key Words

oxidation, aldehydes, esters, vanadium pentoxide, hydrogen peroxide

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ID: J54-Y2000-410