Catalytic Diastereoselective Reductive Claisen Rearrangement
Steven P. Miller and James P. Morken*
*Department of Chemistry, Merkert Chemistry Center, Boston
College, Chestnut Hill, Massachusetts 02467, Email: morken
bc.edu
S. P. Miller, J. P. Morken, Org. Lett., 2002, 4, 2743-2745.
DOI: 10.1021/ol026273b (free Supporting Information)
Abstract
An ester enolate Claisen rearrangement is catalyzed by [(cod)RhCl]2 and MeDuPhos with good yields and diastereocontrol. The mild reaction conditions tolerate base-sensitive functionalities.
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Key Words
Ireland-Claisen Rearrangement, Silanes
ID: J72-Y2002-860
