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A novel pyrrole synthesis

Sameer Agarwal and Hans-Joachim Knölker*

*Institut für Organische Chemie, Technische Universität Dresden, Bergstrasse 66, 01069 Dresden, Email:

S. Agarwal, H.-J. Knölker, Org. Biomol. Chem., 2004, 2, 3060-3062.

DOI: 10.1039/b412206b


A silver(I)-promoted oxidative cyclization of homopropargylamines at room temperature provides pyrroles. Homopropargylamines are readily available by the addition of a propargyl Grignard reagent to Schiff bases.

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Key Words

Pyrroles, Heterocycles

ID: J52-Y2004-740