A New Ketone Synthesis by Palladium-Catalyzed Cross-Coupling Reactions of Esters with Organoboron Compounds
Hiroto Tatamidani, Fumitoshi Kakiuchi and Naoto Chatani*
*Department of Applied Chemistry, Faculty of Engineering, Osaka University, Suita, Osaka 565-0871, Japan, Email: chatanichem.eng.osaka-u.ac.jp
H. Tatamidani, F. Kakiuchi, N. Chatani, Org. Lett., 2004, 6, 3597-3599.
DOI: 10.1021/ol048513o (free Supporting Information)
The palladium-catalyzed coupling of 2-pyridyl esters with organoboron compounds is compatible with various functional groups and proceeds under mild reaction conditions. The coordination of the nitrogen atom to Pd is a key step for an efficient reaction.
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Cross-Coupling, Palladium Catalysis, Aryl Ketones