C1-Symmetric Sulfoximines as Ligands in Copper-Catalyzed Asymmetric Mukaiyama-Type Aldol Reactions
Martin Langner and Carsten Bolm*
*Institut für Organische Chemie der Rheinisch-Westfälischen Technischen
Hochschule Aachen, Landoltweg 1, 52056 Aachen, Germany, Email: carsten.bolm
oc.rwth-aachen.de
M. Langner, C. Bolm, Angew. Chem. Int. Ed., 2004, 43, 5984-5987.
Abstract
The synthesis of new C1-symmetric benzene-bridged aminosulfoximines is described. These aminosulfoximines are capable of serving as efficient ligands in copper-catalyzed enantioselective Mukaiyama-type aldol reactions.
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Key Words
aldol reaction, asymmetric catalysis, copper, N ligands, sulfoximines, Mukaiyama Aldol Addition, β-hydroxy carbonyl compounds
ID: J06-Y2004-860
