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Radical Alkenylation of α-Halo Carbonyl Compounds with Alkenylindiums

Kazuaki Takami, Hideki Yorimitsu and Koichiro Oshima*

*Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan, Email:

K. Takami, H. Yorimitsu, K. Oshima, Org. Lett., 2004, 6, 4555-4558.

DOI: 10.1021/ol048070o


A radical alkenylation reaction of α-halo carbonyl compounds with styrylindium dichloride as well as unactivated alkenylindiums proceeded in the presence of triethylborane. The geometry of the carbon-carbon double bonds was retained. Efficient one-pot strategies were developed.

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Key Words

Alkenylation, Alkenylation of carbonyl compounds, Alkenylindium Compounds

ID: J54-Y2004-1070