Organic Chemistry Portal



Zirconium Tetrachloride (ZrCl4) Catalyzed Highly Chemoselective and Efficient Acetalization of Carbonyl Compounds

Habib Firouzabadi*, Nasser Iranpoor, Babak Karimi

*Department of Chemistry, College of Sciences, Shiraz University, Shiraz 71454, Iran, Email:

H. Firouzabadi, N. Iranpoor, B. Karimi, Synlett, 1999, 321-323.

DOI: 10.1055/s-1999-2605


Zirconium tetrachloride (ZrCl4) is a highly efficient and chemoselective catalyst for the acetalization, and in situ transacetalization of carbonyl compounds under mild reaction conditions.

see article for more examples

Key Words

acetals, zirconium tetrachloride, carbonyl compounds, 1,3-dioxanes, protection

ID: J60-Y1998-320