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Reactions on a Solid Surface. A Simple, Economical and Efficient Friedel-Crafts Acylation Reaction over Zinc Oxide (ZnO) as a New Catalyst

Mona Hosseini Sarvari and Hashem Sharghi*

*Department of Chemistry, Faculty of Science, Shiraz University, Shiraz 71454, I.R. Iran, Email:

M. H. Sarvari, H. Sharghi, J. Org. Chem., 2004, 69, 6953-6956.

DOI: 10.1021/jo0494477


Zinc oxide (ZnO) catalyzes a rapid Friedel-Crafts acylation of various aromatic compounds with acid chlorides in solvent-free conditions at room temperature. The ZnO powder can be reused up to three times after simple washing with dichloromethane.

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Key Words

Friedel-Crafts acylation

ID: J42-Y2004-1220