Reactions on a Solid Surface. A Simple, Economical and Efficient Friedel-Crafts Acylation Reaction over Zinc Oxide (ZnO) as a New Catalyst
Mona Hosseini Sarvari and Hashem Sharghi*
*Department of Chemistry, Faculty of Science, Shiraz University, Shiraz 71454, I.R. Iran, Email: shashemchem.susc.ac.ir
M. H. Sarvari, H. Sharghi, J. Org. Chem., 2004, 69, 6953-6956.
DOI: 10.1021/jo0494477 (free Supporting Information)
Zinc oxide (ZnO) catalyzes a rapid Friedel-Crafts acylation of various aromatic compounds with acid chlorides in solvent-free conditions at room temperature. The ZnO powder can be reused up to three times after simple washing with dichloromethane.
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