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Convenient Transformation of Optically Active Nitroalkanes into Chiral Aldoximes and Nitriles

Constantin Czekelius, Erick M. Carreira*

*Laboratorium für Organische Chemie, ETH Hönggerberg, HCI H335, 8093 Zürich, Switzerland, Email:

C. Czekelius, E. M. Carreira, Angew. Chem. Int. Ed., 2005, 44, 612-615.

DOI: 10.1002/anie.200461879


A convenient, environmentally friendly method for the synthesis of optically active aldoximes and nitriles starting from chiral nitroalkanes was developed.

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Key Words

chirality, nitro compounds, oximes, nitriles, reduction, synthetic methods

ID: J06-Y2005-000