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Reduction of β-Hydroxyketones by SmI2/H2O/Et3N

Todd A. Davis, Pramod R. Chopade, Göran Hilmersson, and Robert A. Flowers, II*

*Department of Chemistry, Lehigh University, Bethlehem, Pennsylvania 18015, Email:

T. A. Davis, P. R. Chopade, G. Hilmersson, R. A. Flowers, II, Org. Lett., 2005, 7, 119-122.

DOI: 10.1021/ol047835p


Reduction of β-hydroxyketones by SmI2/H2O/Et3N provided 1,3-diols in quantitative yields with no byproduct formation.

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Key Words

1,3-Diols, Samarium, Reduction

ID: J54-Y2005-020