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Enantioselective Organocatalyzed α Sulfenylation of Aldehydes

Mauro Marigo, Tobias C. Wabnitz, Doris Fielenbach, Karl Anker Jørgensen*

*The Danish National Research Foundation: Center for Catalysis, Department of Chemistry, Aarhus University, 8000 Aarhus C, Denmark, Email:

M. Marigo, T. C. Wabnitz, D. Fielenbach, K. A. Jorgensen, Angew. Chem. Int. Ed., 2005, 44, 794-797.

DOI: 10.1002/anie.200462101


Sterically encumbered chiral pyrrolidine derivatives are highly efficient organocatalysts for the direct enantioselective α sulfenylation of aldehydes using an electrophilic sulfur source.

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Key Words

α sulfenylation, sulfides, organocatalysis

ID: J06-Y2005-060