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Efficient Stille Cross-Coupling Reaction Catalyzed by the Pd(OAc)2/Dabco Catalytic System

Jin-Heng Li,* Yun Liang, De-Ping Wang, Wen-Jie Liu, Ye-Xiang Xie and Du-Lin Yin

*Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, China, Email:

J.-H. Li, Y. Liang, D.-P. Wang, W.-J. Liu, Y.-X. Xie, D.-L. Yin, J. Org. Chem., 2005, 70, 2832-2834.

DOI: 10.1021/jo048066q


An efficient Pd(OAc)2/Dabco-catalyzed Stille cross-coupling reaction has been developed. Various aryl halides including aryl iodides, aryl bromides, and activated aryl chlorides were coupled efficiently with organotin compounds to afford the corresponding biaryls, alkenes, and alkynes in good to excellent yields.

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Key Words

Stille Coupling

ID: J42-Y2005-390