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Hydroamination/Hydrosilylation Sequence Catalyzed by Titanium Complexes

Andreas Heutling, Frauke Pohlki, Igor Bytschkov, Sven Doye*

*Institut für Reine und Angewandte Chemie, Universität Oldenburg, Carl-von-Ossietzky-Strasse 9-11, 26111 Oldenburg, Germany, Email:

A. Heutling, F. Pohlki, I. Bytschkov, S. Doye, Angew. Chem. Int. Ed., 2005, 44, 2951-2954.

DOI: 10.1002/anie.200462250

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The sequential combination of Ti-catalyzed hydroamination of alkynes followed by the Ti-catalyzed hydrosilylation of the intermediate imines is an efficient one-pot process for the conversion of alkynes and primary amines into secondary amines.

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Key Words

alkynes, arylamines, hydroamination, hydrosilylation, titanium, phenylsilane

ID: J06-Y2005-510