Chemoselective Thioacetalization in Water: 3-(1,3-Dithian-2-ylidene)pentane- 2,4-dione as an Odorless, Efficient, and Practical Thioacetalization Reagent
Dewen Dong,* Yan Ouyang, Haifeng Yu, Qun Liu, Jun Liu, Mang Wang and Jing Zhu
*Department of Chemistry, Northeast Normal University, Changchun, 130024, P. R. China, Email: dongdw663nenu.edu.cn
D. Dong, Y. Ouyang, H. Yu, Q. Liu, J. Liu, M. Wang, J. Zhu, J. Org. Chem., 2005, 70, 4535-4537.
DOI: 10.1021/jo050271y (free Supporting Information)
3-(1,3-dithian-2-ylidene)pentane-2,4-dione has been used as a nonthiolic, odorless 1,3-propanedithiol equivalent in the p-dodecylbenzenesulfonic acid-catalyzed thioacetalization of various aldehydes and ketones in water.
see article for more examples
Y. Ouyang, D. Dong, C. Zheng, H. Yu, Q. Liu, Z. Fu, Synthesis, 2006, 3801-3804.