Synthesis of Lactams via Copper-Catalyzed Intramolecular Vinylation of Amides
Tianshun Hu and Chaozhong Li*
*Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, P. R. China, Email: cligmail.sioc.ac.cn
T. Hu, C. Li, Org. Lett., 2005, 7, 2035-2038.
An intramolecular vinylation of various iodoenamides using CuI as the catalyst and N,N'-dimethylethylenediamine as the ligand led to five- to seven-membered lactams in moderate to excellent yields.
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