Ni(II)-Catalyzed Conia-Ene Reaction of 1,3-Dicarbonyl Compounds with Alkynes
Qiang Gao, Bao-Fu Zheng, Jin-Heng Li and Dan Yang*
*Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, P. R. China, Email: yangdanhku.hk
Q. Gao, B.-F. Zheng, J.-H. Li, D. Yang, Org. Lett., 2005, 7, 2185-2188.
A Ni(II)-catalyzed Conia-ene reaction of various acetylenic 1,3-dicarbonyl compounds has been discovered. The reaction gave mono- and bicyclic olefinic cyclopentantes in good yields in the presence of Ni(acac)2 and Yb(OTf)3.
see article for more examples
Conia-Ene Reactions, Active methylenes, Cyclopentanes