Copper- and Ligand-Free Sonogashira Reaction Catalyzed by Pd(0) Nanoparticles at Ambient Conditions under Ultrasound Irradiation
Atul R. Gholap, K. Venkatesan, Renu Pasricha, Thomas Daniel, Rajgopal J. Lahoti and Kumar V. Srinivasan*
*Organic Chemistry; Technology Division, and Centre for Material
Characterization, National Chemical Laboratory, Dr. Homi Bhabha Road, Pune - 411
008, India, Email: kv.srinivasan
ncl.res.in
A. R. Gholap, K. Venkatesan, R. Pasricha, T. Daniel, R. J. Lahoti, K. V. Srinivasan, J. Org. Chem., 2005, 70, 4869-4872.
DOI: 10.1021/jo0503815
Abstract
The Sonogashira reaction proceeds efficiently at ambient temperature in acetone or 1,3-di-n-butylimidazolium tetrafluoroborate ([bbim]BF4, a room-temperature ionic liquid) under ultrasound irradiation in the absence of a copper cocatalyst and a phosphine ligand.
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Key Words
Sonogashira Coupling, Ultrasound, Sonochemistry, Ionic Liquids
ID: J42-Y2005-560
