A Highly Efficient Method for the Reductive Etherification of Carbonyl Compounds with Triethylsilane and Alkoxytrimethylsilane Catalyzed by Iron(III) Chloride
Katsuyuki Iwanami, Hana Seo, Yuki Tobita, Takeshi Oriyama*
*Department of Environmental Sciences, Faculty of Science, Ibaraki
University, 2-1-1 Bunkyo, Mito 310-8512, Japan, Email: tor
mx.ibaraki.ac.jp
K. Iwanami, H. Seo, Y. Tobita, T. Oriyama, Synthesis, 2005, 183-186.
DOI: 10.1055/s-2004-834942
Abstract
Facile reductive etherification of carbonyl compounds can be conveniently performed by reaction with triethylsilane and alkoxytrimethylsilane catalyzed by iron(III) chloride. The corresponding alkyl ethers, including benzyl and allyl ethers, of the reduced alcohols were obtained in good to excellent yields under mild reaction conditions.
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Key Words
reductive etherification, benzyl ethers, iron(III) chloride, alkoxytrimethylsilane, triethylsilane, carbonyl compounds
ID: J66-Y2005-670
