Recyclable and Reusable Pd(OAc)2/DABCO/PEG-400 System for Suzuki-Miyaura Cross-Coupling Reaction
Jin-Heng Li,* Wen-Jie Liu and Ye-Xiang Xie
*Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, China, Email: jhlihunnu.edu.cn
J.-H. Li, W.-J. Liu, Y.-X. Xie, J. Org. Chem., 2005, 70, 5409-5412.
DOI: 10.1021/jo050353m (free Supporting Information)
Pd(OAc)2/DABCO is a stable and efficient catalytic system for Suzuki-Miyaura cross-coupling reactions using PEG-400 as the solvent. Moreover, the Pd(OAc)2/DABCO/PEG-400 system could be recycled and reused five times without any loss of catalytic activity for aryl iodides and bromides.
see article for more examples
see article for more reactions
W.-J. Liu, Y.-X. Xie, Y. Liang, J.-H. Li, Synthesis, 2006, 860-864.