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Recyclable and Reusable Pd(OAc)2/DABCO/PEG-400 System for Suzuki-Miyaura Cross-Coupling Reaction

Jin-Heng Li,* Wen-Jie Liu and Ye-Xiang Xie

*Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, China, Email:

J.-H. Li, W.-J. Liu, Y.-X. Xie, J. Org. Chem., 2005, 70, 5409-5412.

DOI: 10.1021/jo050353m (free Supporting Information)


Pd(OAc)2/DABCO is a stable and efficient catalytic system for Suzuki-Miyaura cross-coupling reactions using PEG-400 as the solvent. Moreover, the Pd(OAc)2/DABCO/PEG-400 system could be recycled and reused five times without any loss of catalytic activity for aryl iodides and bromides.

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Reusable and Efficient Pd(OAc)2/TBAB/PEG-400 System for Suzuki-Miyaura Cross-Coupling Reaction under Ligand-Free Conditions

W.-J. Liu, Y.-X. Xie, Y. Liang, J.-H. Li, Synthesis, 2006, 860-864.

Key Words

Suzuki Coupling

ID: J42-Y2005-770