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Highly Enantioselective Catalytic Fluorination and Chlorination Reactions of Carbonyl Compounds Capable of Two-Point Binding

Norio Shibata, Junji Kohno, Kazumi Takai, Takehisa Ishimaru, Shuichi Nakamura, Takeshi Toru, Shuji Kanemasa

*Department of Applied Chemistry, Graduate School of Engineering, Nagoya Institute of Technology, Gokiso, Showa-ku, Nagoya 466-8555, Japan, Email: nozshibanitech.ac.jp

N. Shibata, J. Kohno, K. Takai, T. Ishimaru, S. Nakamura, T. Toru, S. Kanemasa, Angew. Chem. Int. Ed., 2005, 44, 4204-4207.

DOI: 10.1002/anie.200501041 (free Supporting Information)


Abstract

Catalytic enantioselective fluorination and chlorination reactions of carbonyl compounds were achieved with high enantioselectivity by the use of a dbfox-NiII complex.

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Key Words

asymmetric amplification, asymmetric synthesis, enantioselectivity, fluorination, chlorination, halogenation


ID: J06-Y2005-820