A Simple and Efficient Heterogeneous Procedure for Thioacetalization of Aldehydes and Ketones
Mohammed Hashmat Ali*, Maria Goretti Gomes
*Chemistry Department, Southeast Missouri State University, Cape Girardeau,
MO 63701, USA, Email: mhali
semo.edu
M. H. Ali, M. G. Gomes, Synthesis, 2005, 1326-1332.
DOI: 10.1055/s-2005-865303
Abstract
A new procedure for the protection of aldehydes and ketones as thioacetals promoted by catalytic amount of p-toluenesulfonic acid and silica gel has been developed. This procedure offers versatility, short reaction time, excellent yield, and is easy to carry out. A simple filtration followed by removal of solvent in most cases produces pure product.
see article for more examples
Key Words
thioacetals, 1,3-dithiolanes, silica gel, heterogeneous, ketones, aldehydes
ID: J66-Y2005-920
