Organic Chemistry Portal

Abstracts

Search:

Synthesis of Fused Bicyclic Imidazoles by Sequential Van Leusen/Ring-Closing Metathesis Reactions

Vijaya Gracias,* Alan F. Gasiecki and Stevan W. Djuric

*Scaffold-Oriented Synthesis, Medicinal Chemistry Technologies, Abbott Laboratories, R4CP, AP10, 100 Abbott Park Road, Abbott Park, Illinois 60064-6099, Email: vijaya.graciasabbott.com

V. Gracias, A. F. Gasiecki, S. W. Djuric, Org. Lett., 2005, 7, 3183-3186.

DOI: 10.1021/ol050852+



see article for more reactions

Abstract

Fused bicyclic imidazole rings have been prepared in good yields by a sequence of the van Leusen three-component reaction and the ring-closing metathesis reaction.

see article for more reactions


Are you satisfied with our abstracts? Please donate to help us make more chemical information openly available:


Key Words

Van Leusen Imidazole Synthesis, Ring Closing Metathesis, Imidazole Derivatives, Heterocycles


ID: J54-Y2005-960