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Chiral Boron-Bridged Bisoxazolines: Readily Available Anionic Ligands for Asymmetric Catalysis

Clément Mazet, Valentin Köhler, Andreas Pfaltz*

*Department of Chemistry, University of Basel, St. Johanns Ring 19, 4056 Basel, Switzerland, Email:

C. Mazet, V. Koehler, A. Pfaltz, Angew. Chem. Int. Ed., 2005, 44, 4888-4891.

DOI: 10.1002/anie.200501305 (free Supporting Information)


A new class of anionic, boron-bridged analogues of the box ligands was developed. These borabox ligands showed a considerable potential for asymmetric cyclopropanation and desymmetrizations of meso diols.

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Key Words

acylation, desymmetrization of diols, asymmetric catalysis, copper, diazo compounds, N ligands, cyclopropanation

ID: J06-Y2005-1070