Highly Chemoselective Addition of Amines to Epoxides in Water
Najmodin Azizi and Mohammad R. Saidi*
*Department of Chemistry, Sharif University of Technology, P.O. Box 11465-9516, Tehran, Iran, Email: saidisharif.edu
N. Azizi, M. R. Saidi, Org. Lett., 2005, 7, 3649-3651.
DOI: 10.1021/ol051220q (free Supporting Information)
The mild aminolysis of a variety of epoxides in water gave β-amino alcohols with high selectivity and in excellent yields in the absence of any catalyst.
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