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Palladium-Catalyzed One-Pot Synthesis of Highly Substituted Furans by a Three-Component Annulation Reaction

Xin-hua Duan, Xue-yuan Liu, Li-na Guo, Meng-chun Liao, Wei-Min Liu and Yong-min Liang*

State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P.R. China, Email:

X.-H. Duan, X.-Y. Liu, L.-N. Guo, M.-C. Liao, W.-M. Liu, Y.-M. Liang, J. Org. Chem., 2005, 70, 6980-6983.

DOI: 10.1021/jo050908d (free Supporting Information)


A new three-component cyclization catalyzed by palladium produces polysubstituted furans in good yields from readily available substrates. A mechanism is proposed.

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Key Words

Furans, Multicomponent Reactions

ID: J42-Y2005-1250