Cu(I)-Catalyzed Highly Exo-selective and Enantioselective [3 + 2] Cycloaddition of Azomethine Ylides with Acrylates
Wenzhong Gao, Xumu Zhang and Malati Raghunath
*104 Chemistry Building, Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania, Email: xumuchem.psu.edu
W. Gao, X. Zhang, M. Raghunath, Org. Lett., 2005, 7, 4241-4244.
A Cu(I)-catalyzed enantioselective 1,3-dipolar cycloaddition of azomethine ylides to acrylates with high exo/endo selectivity and up to 98% enantiomeric excess has been developed.
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1,3-dipolar cycloaddition, N-Heterocycles