Palladium-Catalyzed Addition of Arylboronic Acids to Aldehydes
Tetsuya Yamamoto, Tetsuo Ohta* and Yoshihiko Ito
*Department of Molecular Science and Technology, Faculty of Engineering, Doshisha University, Kyotanabe, Kyoto 610-0394, Japan, Email: totamail.doshisha.ac.jp
T. Yamamoto, T. Ohta, Y. Ito, Org. Lett., 2005, 7, 4151-4155.
DOI: 10.1021/ol051501y (free Supporting Information)
A palladium(0) complex with chloroform is able to catalyze the addition of arylboronic acids to aldehydes in the presence of a base, affording the corresponding secondary alcohols in good yields. A catalytic amount of chloroform seems to be essential for this reaction.
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