A new reactivity pattern for vinyl bromides: cine-substitution via palladium catalysed C-N coupling/Michael addition reactions
Michael C. Willis, Jay Chauhan and William G. Whittingham
*Department of Chemistry, University of Bath, BA2 7AY, UK, Email: m.c.willis
bath.ac.uk
M. C. Willis, J. Chauhan, W. G. Whittinham, Org. Biomol. Chem., 2005, 3, 3094-3095.
DOI: 10.39/b508464d
Abstract
Michael adducts are provided by a reaction of alkylidene malonates with enamines, which are generated from vinyl bromides and pyrrolidine by a prior palladium-catalysed C-N bond formation.
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Key Words
Buchwald-Hartwig Reaction, Michael Addition
ID: J52-Y2005-1550
