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Practical and Efficient Suzuki-Miyaura Cross-Coupling of 2-Iodocycloenones with Arylboronic Acids Catalyzed by Recyclable Pd(0)/C

François-Xavier Felpin

*Université Bordeaux-I, Laboratoire de Chimie Organique et Organométallique, 351 Cours de la Libération, 33405 Talence Cedex, France, Email:

F.-X. Felpin, J. Org. Chem., 2005, 70, 8575-8578.

DOI: 10.1021/jo051501b (free Supporting Information)


A mild, Pd/C-catalyzed Suzuki-Miyaura coupling of 2-iodocycloenones with arylboronic acids is described. Notably, the procedure features inexpensive reagents, reactions under air, and solvents with low toxicity. In addition, the Pd/C could be reused at least five times.

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Key Words

Suzuki Coupling, Olefination

ID: J42-Y2005-1590